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Identifies ACTH-producing cells as well as tumors that may secrete ACTH in the setting of paraneoplastic syndromes. Assists in the evaluation and classification of pituitary neoplasms and other pituitary conditions.Reacts with ACTH-producing cells and some other tumors causing paraneoplastic syndromes by secreting ACTH, helpful in classifying pituitary tumors and pituitary diseases.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.