Marks cells involved in regulating prostate epithelial growth and is expressed in a subset of carcinomas, including those of the prostate, breast, and salivary gland. In untreated prostate cancer, AR positivity is associated with potential responsiveness to hormonal therapy, whereas in hormone-refractory disease, AR expression is linked to poorer prognosis.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.