Arginase-1 is a highly sensitive and specific marker for hepatocellular differentiation. It is strongly expressed in normal hepatocytes and hepatocellular carcinoma, and can help distinguish HCC from metastatic carcinomas involving the liver.A highly sensitive and specific marker of benign and malignant hepatocytes and hepatocellular carcinoma.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumorblock preferred.
Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.