BCR/ABL1 Kinase Domain Mutation

RT-PCR and sequencing of the BCR-ABL1 fusion transcript for qualitative detection of mutations associated with resistance to Gleevec (imatinib) and other tyrosine kinase inhibitors. Analysis includes detection of all mutations recommended by guidelines, including the common T315I, Y253H, E255K/V, F359V/C/I, F317L/V/I/C, T315A, and V299L.

Turnaround Time
11 days
Specimen Requirements
  • Peripheral blood: 5 mL in EDTA tube.
  • Bone marrow: 2 mL in EDTA tube.

Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Ship same day as drawn whenever possible; specimens <7 days old preferred.

CPT Codes