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Detects a glycoprotein expressed on the surface and in the cytoplasm of most epithelial cells, excluding superficial squamous cells, hepatocytes, and parietal cells. It is positive in most adenocarcinomas, does not stain mesothelial cells, and is generally negative in mesotheliomas, helping to distinguish adenocarcinomas from pleural mesotheliomas.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.