Identifies a transcription factor localized to the nucleus of the cell and the product of the gene first discovered in Burkitt's lymphoma. The protein is overexpressed as a result of chromosomal translocation involving chromosome 8 and overexpression is present in 20-30% of breast cancer cases, 90% of Burkitt's lymphoma, and over 50% in a subset of cases of diffuse large B-cell lymphoma. It is also positive in radiation-associated angiosarcoma.

Turnaround Time
24 hrs
Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342 x 1 or 88341 x 1