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PCR assay for fragment analysis of exon 9 of the CALR (calreticulin) gene for enhanced detection of low levels of insertion/deletion mutations, which generally appear to be mutually exclusive with JAK2 and MPL mutations. This aids in the specific diagnosis of a myeloproliferative neoplasm and distinguishes from a benign reactive process.
Whole blood (3-5 mL), Bone marrow(1-2 mL), in Lavender-top (EDTA) tube.
Use cold pack for transport but not in direct contact with specimen. Ship same day as drawn whenever possible.