A protein kinase transmembrane receptor that is expressed in tissues and cells such as tissue mast cells, skin basal cells, melanocytes, breast glandular epithelial cells, dermal sweat gland, esophageal glands, and testicular and ovarian interstitial cells. It is a marker of gastrointestinal stromal tumors and is also expressed in melanomas, breast carcinomas, and small cell lung carcinoma. A mutant form of gastrointestinal stromal tumor is the target of imatinib mesylate therapy.

Turnaround Time
Tech-Only (stain only): 24 hrs
Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342 x 1 or 88341 x 1