CD11c

Expressed on activated CD4/CD8+ T cells, granulocytes, lymphocytes, macrophages, and NK cells. In disease, it is detected in AML (M4/M5), hairy cell leukemia, lymphoplasmacytic lymphoma, SLL, splenic lymphoma, Langerhans cell histiocytosis, sinus histiocytosis, psoriatic skin lesions, and some follicular lymphomas.

Synonyms

Turnaround Time

24 Hrs

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.

Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.

Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

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Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes

88342x1 or 88341x1