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Identifies the interleukin-3 receptor and labels plasmacytoid dendritic cells. It is useful in diagnosing neoplasms derived from these cells and is also expressed at variable intensity in all classical hairy cell leukemia, most B-ALLs, and in a subset of AMLs. It is also useful for diagnosing reactive conditions such as histiocytic necrotizing lymphadentis.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.