A cytoplasmic and cell-surface associated protein that plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is strongly expressed by granulocytes at the promelocyte and later stages, and to a lesser degree on monocytes/histiocytes. It is also expressed in Reed-Sternberg cells and some epithelial cells and occasionally in large cell lymphomas of both B- and T- phenotypes, and is useful in identifying Hodgkin lymphoma.

Turnaround Time
24 hrs
Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342 x 1 or 88341 x 1