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A transmembrane protein mediating phagocytosis by neutrophils and monocytes. Marks benign and malignant follicular dendritic cells, and is also expressed on erythrocytes, B cells, some T cells, monocytes, macrophages, neutrophils, eosinophils, and glomerular podocytes. Useful for identifying follicular dendritic cells, diagnosing MALT lymphoma, and studying inflammatory disorders.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.