Identifies the transferrin receptor responsible for iron uptake in cells. CD71 is a useful marker for detecting erythroid precursors without interference from mature erythrocytes and aids in diagnosing erythroid leukemia, benign erythroid proliferative disorders, and myelodysplastic syndromes. It specifically highlights erythroid precursors in both normal and abnormal bone marrow.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.