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Detects a tight junction protein expressed in epithelial cells. Useful for identifying epithelial differentiation and certain carcinomas, including distinguishing skin adnexal tumors and some colorectal carcinomas.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack but not in direct contact with specimen. Not suitable for freeze & hold option.