Claudin-4

Marks a tight junction protein expressed in most epithelial cells. Useful for identifying epithelial differentiation and distinguishing carcinomas, including differentiating adenocarcinomas from mesotheliomas.

Synonyms
Turnaround Time
24 Hrs
Methodology
IHC
Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.

Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked.

Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack but not in directcontact with specimen. Not suitable for freeze & hold option.

CPT Codes
88342x1 or 88341x1