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Detects Epstein-Barr virus–encoded RNA within infected cells, identifying all latent EBV-infected cells, including EBV-positive lymphoblastoid cell lines and B-cell immunoblasts in infectious mononucleosis. It is also positive in EBV-associated undifferentiated nasopharyngeal carcinomas and Reed-Sternberg cells in nearly all EBV-associated Hodgkin lymphoma cases.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.