.png)
Detects deletions or mutations in exon 19 of the EGFR gene, which are common activating mutations in non-small cell lung carcinoma (NSCLC). These mutations predict sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib, erlotinib, and afatinib, aiding in targeted therapy selection and prognosis assessment.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.