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Detects a 15 kDa protein expressed in apocrine epithelia, lacrimal, ceruminous, and Moll’s glands, as well as serous cells of salivary, tracheal, and bronchial glands. GCDFP-15 is used to identify breast carcinoma, sweat gland carcinoma, and a subset of salivary gland carcinomas. It may also be expressed in about 10% of primary lung adenocarcinomas.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.