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A transmembrane protein that facilitates glucose transport in mammalian cells. GLUT1 is expressed in colon, lung, stomach, esophagus, and breast tissues. Overexpression is associated with aggressive behavior in cancers such as breast, renal, and bladder carcinoma, and it is useful in distinguishing malignant mesothelioma from reactive mesothelial proliferations.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.