HPL = Human Placental Lactogen

A hormone produced by placental syncytiotrophoblasts, used as a tissue marker for gestational trophoblastic tumors and to assess placental function. It is clinically valuable in evaluating patients with suspected trophoblastic disease or pregnancy-related complications, including hypertensive disorders of pregnancy.

Synonyms
Turnaround Time
24 Hrs
Methodology
IHC
Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.

Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.

Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342x1 or 88341x1