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This antibody reacts with immunoglobulin Ig delta chains, cytoplasmic proteins strongly expressed by naive/mantle zone B-cells and a small subset of plasma cells, and weakly expressed by germinal center B cells. This antibody is useful in identifying leukemias, plasmacytomas, and B-cell lineage lymphomas, as well as a subset of B-cell non-Hodgkin lymphomas and normal mantle zone B-lymphocytes.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.