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Identifies low–molecular-weight cytokeratins found in most simple epithelial cells and their derived carcinomas. It is expressed in glandular and ductal epithelium of organs such as the liver, pancreas, lung, breast, and gastrointestinal tract, and is useful in confirming epithelial origin in poorly differentiated tumors.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.