Keratin AE1/AE3

A blend of two monoclonal antibodies targeting acidic and basic cytokeratins, expressed in most epithelial tumors. Useful for confirming carcinoma, distinguishing epithelial from non-epithelial tumors, and identifying carcinomas in undifferentiated malignancies.

Synonyms
Pancytokeratin
Turnaround Time
24 Hrs
Methodology
IHC
Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.

Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.

Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342x1 or 88341x1