.png)
Identifies a cysteine-rich protein involved in hematopoietic development, expressed in germinal center B-cells, endothelial cells, and hematopoietic precursors. It is useful in distinguishing germinal center B-cell–type diffuse large B-cell lymphomas (DLBCLs) from non-germinal center types and is rarely expressed in mature T, NK, or plasma cell neoplasms.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.