Mammaglobin

Identifies a breast-associated glycoprotein that is a sensitive and specific marker of carcinomas primary to the breast. In normal breast tissue, this antibody labels breast ductal and lobular epithelial cells; in tumor cells, it reacts with all types of breast adenocarcinoma regardless of tumor differentiation and type. This protein can also be expressed in a subset of salivary gland tumors as well as ovarian carcinomas, but adenocarinomas from other organs rarely express mammaglobin. It can help in the identification of primary cites of carcinomas.