Identifies a cell surface glycoprotein expressed in mesothelial cells and malignant mesothelioma, as well as in various carcinomas including ovarian, breast, pancreatic, and squamous tumors. Less specific for mesothelioma compared to WT-1, calretinin, and podoplanin.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.