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Identifies a peroxidase enzyme expressed at high levels in granulocytes involved in phagocytic lysis of foreign particles. Myeloid cells of neutrophilic and eosinophilic types show strong cytoplasmic staining in normal tissues and myeloproliferative disorders. MPO is useful in distinguishing myeloid from lymphoid leukemias.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.