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This antibody detects the two isoforms of p63 being the dominant form in basal and myoepithelial cells and in squamous cell carcinomas of the lung and other sites. Because p40 is more specific than p63, its use helps prevent misinterpreting p63-positive adenocarcinomas as squamous cell carcinomas.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.