Bi-directional sequencing analysis of exons 12and 18 of the PDGFRA gene, detected in gastrointestinal stromal tumors(GISTs) including the common TKI-resistance mutation D842V.
Formalin-fixed, paraffin-embedded (FFPE) solid tumor tissue block (preferred) or slides (1 H&E slide, plus 5-10 unstained slides cut at 5+ microns). Please use positively charged slides and 10% NBF fixative. Do not use zinc fixatives.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.