.png)
Identifies a phosphorylated form of histone H3 associated with chromatin condensation during mitosis. PHH3 is a sensitive marker for highlighting mitotic figures and is widely used to assess tumor proliferative activity and improve accuracy in mitotic counting in various neoplasms.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.