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Identifies a nuclear transcription factor involved in pituitary development and hormone regulation. PIT-1 is expressed in somatotroph, lactotroph, and thyrotroph cells and is useful for classifying pituitary adenomas based on lineage differentiation.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.