All Tests

Prostate Specific Acid Phosphatase (PSAP)

Identifies a 100 kDa glycoprotein found in high concentration in prostate tissue and its secretions. It is specific for benign and malignant prostatic epithelial cells, with negative staining in prostatic stroma, urethra, and basal cells. PSAP expression may be lost in inflamed or infarcted tissue and in areas of squamous metaplasia. Nearly all metastatic prostatic carcinomas retain PSAP expression, making it a reliable marker for confirming prostatic origin.

Synonyms
PAPH
Turnaround Time
24 Hrs
Methodology
IHC
Specimen Requirements

Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue block

Alternative specimen: 

  • One (1) unbaked, unstained slide for H&E staining (required)
  • Two to three (2–3) positively charged unstained slides per test/antibody ordered
  • All slides must be cut at 4–5 microns

Labeling Requirements: 

  • Block and slide identifiers must be clearly written
  • All identifiers must match exactly with the specimen ID and labeling on the requisition

‍

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342x1 or 88341x1