All Tests

Prostate Specific Antigen (PSA)

Identifies a glycoprotein localized to the cytoplasm of acinar and ductal epithelial cells of normal, benign, and malignant prostate tissue. It is a highly sensitive and specific marker for metastatic prostate adenocarcinoma. PSA produced by prostate cancer is immunologically and biochemically similar to that of normal prostate. Because it does not react with non-prostatic tumors, PSA is valuable for determining whether an isolated metastasis is of prostatic origin.

Synonyms
Prostate-Specific Antigen
Turnaround Time
24 Hrs
Methodology
IHC
Specimen Requirements

Preferred specimen: Formalin-fixed, paraffin-embedded (FFPE) tissue block

Alternative specimen: 

  • One (1) unbaked, unstained slide for H&E staining (required)
  • Two to three (2–3) positively charged unstained slides per test/antibody ordered
  • All slides must be cut at 4–5 microns

Labeling Requirements: 

  • Block and slide identifiers must be clearly written
  • All identifiers must match exactly with the specimen ID and labeling on the requisition
Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Codes
88342x1 or 88341x1