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DNA-based next-generation sequencing designed to target abnormalities in single-nucleotide and indels in434 genes, associated with cancers of the lung, pancreas, brain, colon, breast,ovary, endometrium, thyroid, head and neck, and soft tissue (sarcoma and GIST).In addition, the test is designed to detect microsatellite instability (MSI),tumor mutation burden (TMB) and homologous recombination deficiency(HRD). The provided information helps in determining prognosis, designing a therapeutic approach and predicting response to therapy.
Formalin-fixed, paraffin-embedded (FFPE): 1 H&E slide plus 6-8, at 5 or more microns fix with 10% NBF fixative. Please circle tumor for microdissection. Alternatively, the FFPE block can be sent for tumor circling and cutting at our laboratory.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.