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T-cell receptor delta (TCR delta) is used as a phenotypic marker for TCR delta-expressing T-cells. TCR is a heterodimer composed of either alpha/beta or gamma/delta. TCR delta is expressed by thymocytes and a majority of peripheral (gamma/delta TCR-bearing) T-cells. Evaluation may help in the differential diagnosis of T-cell lymphomas.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.