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Identifies a specialized DNA polymerase present in immature pre-B and pre-T lymphoid cells, as well as most precursor B- and T-lymphoblastic leukemias/lymphomas. Useful for distinguishing lymphoblastic lymphoma from Burkitt lymphoma, with occasional aberrant expression in some acute myeloid leukemias.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.