Identifies Thymidylate Synthase (TS), a protein targeted by fluoropyrimidine chemotherapies. TS expression can help predict response to 5-FU–based treatments in breast, colorectal, gastric, head, and neck cancers.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.