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Identifies a nuclear transcription factor primarily expressed in lung and thyroid neoplasms. It is present in most lung carcinomas (non-neuroendocrine and endocrine) and nearly all thyroid carcinomas except anaplastic types. This marker is useful in distinguishing primary from metastatic carcinomas, particularly in the lung.
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred.
Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked.
Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.